Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
TNFSF13B Q9Y275 TNF superfamily member 13b 0.98 0.460 0.731
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
STAP1 Q9ULZ2 signal transducing adaptor family member 1 Receptor 1.7E-05 0.792 0.231
SREBF2 Q12772 sterol regulatory element binding transcription factor 2 0.21 0.566 0.577
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SELE P16581 selectin E 7.9E-10 0.447 0.808
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
PON2 Q15165 paraoxonase 2 5.4E-05 0.566 0.808
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PLA2G7 Q13093 phospholipase A2 group VII Enzyme 5.3E-22 0.537 0.769
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
OLR1 P78380 oxidized low density lipoprotein receptor 1 7.2E-03 0.544 0.769
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885